![]() One 1999 study found that participants lost 0.4 pounds on average over the course of 4 weeks. ![]() Some people didn’t lose any weight at all, and losing weight was more likely for nonsmokers.įluoxetine (Prozac) is also associated with small weight loss side effects. The average weight lost on bupropion varied widely in participants, from as little as half a pound to 7.1 pounds over 2 years. ![]() Research published in 2014 suggests that bupropion (Wellbutrin) can lead to weight loss. Weight gain may be the more common side effect of antidepressants.Īntidepressants that have been linked to weight loss include: When weight loss occurs as a side effect, it’s typically minimal. Antidepressants aren’t approved as a weight-loss method by the Food and Drug Administration (FDA). Weight loss isn’t one of the most common or serious side effects of antidepressants. adults over age 18 have used antidepressants in the past 30 days. ![]() Along with talk therapy and cognitive behavioral therapy (CBT), antidepressants are considered the gold standard for treating mental health conditions such as anxiety, depression, bipolar disorder, and others.
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